منابع مشابه
Crossing over without Chiasmatype?
In a recent number of this journal Professor RICHARD GOLDSCHMIDT has a paper (1917) , “Crossing over ohm Chktsmtypie?“, in which he develops a hypothesis to account for crossing over without recourse to the chiasmatype theory of JANSSENS (which, according to GOLDSCHMIDT, “ziemlich in der Luft schwebt”), or to any similar process. The argument is based on the “von jedermann anerkannten Vorausset...
متن کاملCrossing Over…Markov Meets Mendel
Chromosomal crossover is a biological mechanism to combine parental traits. It is perhaps the first mechanism ever taught in any introductory biology class. The formulation of crossover, and resulting recombination, came about 100 years after Mendel's famous experiments. To a great extent, this formulation is consistent with the basic genetic findings of Mendel. More importantly, it provides a ...
متن کاملCrossing over to let go
A function for multisite phosphorylation Many transcription factors are regulated by phosphorylation on multiple residues. Mylona et al. analyzed multisite phosphorylation in the transcription factor Elk-1 and showed that it may protect against excessive activation (see the Perspective by Whitmarsh and Davis). Phosphorylation by the kinase ERK2 occurred at eight sites, but the sites were phosph...
متن کاملDouble Crossing over in Neurospora.
CROSSOVER involves exchange of genetic material between only two of the A four products of meiosis. We should like to know whether there are any special properties of these two strands of the tetrad which enable them to participate in crossing over. Such knowledge might help us understand the mechanics of the crossing over process and would perhaps shed some light on the physical nature of the ...
متن کاملChromosome Structure and Crossing Over.
A major obstacle to understanding classical genetic crossing over in higher organisms has been the lack of sufficient knowledge concerning the structure of chromosomes. Without accurate information, in particular, as to how the hereditary substance (DNA) is built into the chromosome, it may be premature to devise models depicting how that material may be recombined in crossing over. In recent y...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2004
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm1294